Glomerular Filtration Rate (GFR) is the description of the flow rate of filtered fluid through the kidneys. The fluid is filtered from the kidneys glomerular capillaries into Bowman's capsule per unit time. Overall GFR is equal to the clearance rate when any solute is filtered but not reabsorbed or secreted by the kidneys. GFR is recorded in volume per unit time, for example, milliliters per minute (mL/min) with the formula being: GFR = [Urine Concentration multiplied by Urine Flow] / Plasma Concentration. This formula is used only when GFR Calculation is equal to clearance rate. When measured the normal range of GFR when adjusted for body surface area is 100-130ml/min/1.73m2 for adult males and females. For children the range is 110ml/min/1.73m2 until the age of 2 years.
STAGES OF CHRONIC KIDNEY DISEASE AND MANAGEMENT:
| Stage: | GFR Rate: | Description: | Management: |
| 1 | 90 + | Normal renal function | Observation and control of blood pressure |
| 2 | 60-89 | Mildly reduced renal function | Observation, control of blood pressure and cardiovascular risk factors. |
| 3 | 45-59 | Moderate decrease in renal function | Observation, control of blood pressure and cardiovascular risk factors. |
| 3b. | 30-44 | Moderate decrease in renal function | Observation, control of blood pressure and cardiovascular risk factors. |
| 4 | 15-29 | Severely reduced renal function. | Planning for renal failure. |
| 5 | <15 | Very severe renal failure | Transplant or dialysis |
POPULATION MEAN ESTIMATED GLOMERULAR FILTRATION RATES:
| Age in Years: | Mean eGFR |
| 20-29 | 116 mL/min/1.73 m2 |
| 30-39 | 107 mL/min/1.73 m2 |
| 40-49 | 99 mL/min/1.73 m2 |
| 50-59 | 93 mL/min/1.73 m2 |
| 60-69 | 85 mL/min/1.73 m2 |
| 70+ | 75 mL/min/1.73 m2 |
*This GFR Calculator is for educational uses only and should not be used in an emergency or for the treatment of medical conditions. If you feel that you have concerns over your health please consult your doctor.
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